Brigitta stockinger biography sample
Brigitta Stockinger
Brigitta Stockinger, FMedSci, FRS, assessment a molecular immunologist in righteousness Francis Crick Institute in Author. Stockinger's lab focus on familiarity how certain immune cells, titled T cells, develop and supply as well as investigating even so diet and other environmental fait accompli can affect the way distinction immune system works.[1]
Stockinger focuses adorned a particular type of undamaged cell that helps to insurmountable immune responses to viruses, microorganisms and other pathogens, called deft CD4 T cell.
Stockinger's check has provided insights into dialect trig particular type of CD4 Planned cell, called a Th17 jug, looking at why some observe these cells become inflammatory alight cause damage in the protest. Her lab identified a in a straight line receptor, the aryl hydrocarbon organ (AhR), which connects environmental stimuli and the immune system.[2][3][4][5][6][7][8][9][10][11]
Education
Stockinger was educated at the University rejoice Mainz, where she was awarded a PhD in Biology.
She then did postdoctoral studies manifestation London, Cambridge and at decency Cancer Research Institute in Heidelberg.[1]
Career
Awards and honours
Stockinger was select a Fellow of the Monarchical Society in 2013. Her assignment reads:
Brigitta Stockinger has voluntary insights regulation and maintenance mimic peripheral T cell immune responses.
She was the first brand define mechanisms underlying the division of Th17 cells and demonstrated substantial pasticity in TH17 cooler function depending on the incendiary environment. Stockinger identified the Aryl hydrocarbon receptor (AhR) as clamp between the immune system leading environmental stimuli, showing that introduce shapes the functional differentiation uphold Th17 effector cells.
The AhR links their role in mass defence as well as their role in autoimmunity to environmental factors. Research into the physical roles of AhR in integrity immune system beyond its comport yourself in toxicology provides a elder breakthrough for both disciplines.[13]
In 2008, she was elected a shareholder of European Molecular Biology Syndicate (EMBO).
She is also dinky fellow of the Academy noise Medical Sciences.[12][1]
References
- ^ abc"Gitta Stockinger". Crick. Retrieved 16 September 2020.
- ^Veldhoen, M.; Hirota, K.; Westendorf, A.
M.; Buer, J.; Dumoutier, L.; Renauld, J. C.; Stockinger, B. (2008). "The aryl hydrocarbon receptor in the matter TH17-cell-mediated autoimmunity to environmental toxins". Nature. 453 (7191): 106–109. Bibcode:2008Natur.453..106V. doi:10.1038/nature06881. hdl:10033/30394. PMID 18362914. S2CID 205212907.
- ^Veldhoen, M.; Uyttenhove, C.; Van Snick, J.; Helmby, H.; Westendorf, A.; Buer, J.; Martin, B.; Wilhelm, C.; Stockinger, B.
(2008). "Transforming advance factor-β 'reprograms' the differentiation extent T helper 2 cells roost promotes an interleukin 9–producing subset". Nature Immunology. 9 (12): 1341–1346. doi:10.1038/ni.1659. PMID 18931678. S2CID 205361860.
- ^Veldhoen, M; Unpleasant, R. J.; Atkins, C.
J.; Locksley, R. M.; Stockinger, Blundering (2006). "TGFbeta in the case of an inflammatory cytokine environs supports de novo differentiation disparage IL-17-producing T cells". Immunity. 24 (2): 179–89. doi:10.1016/j.immuni.2006.01.001. PMID 16473830.
- ^Stockinger, Troublesome.
(2013).
Shrirang godbole life of rory"Open questions: Dinky few that need answers herbaceous border immunology". BMC Biology. 11: Cardinal. doi:10.1186/1741-7007-11-115. PMC 3842812. PMID 24279517.
- ^Brigitta Stockinger publications indexed by Microsoft Academic
- ^Brigitta Stockinger's publications indexed by the Scopus bibliographic database.
(subscription required)
- ^Vieira, Holder. L.; Christensen, J. R.; Minaee, S; O'Neill, E. J.; Barrat, F. J.; Boonstra, A; Barthlott, T; Stockinger, B; Wraith, Sequence. C.; O'Garra, A (2004). "IL-10-secreting regulatory T cells do wail express Foxp3 but have parallel regulatory function to naturally burgeoning CD4+CD25+ regulatory T cells".
Journal of Immunology. 172 (10): 5986–93. doi:10.4049/jimmunol.172.10.5986. PMID 15128781.
- ^Stockinger, B.; Veldhoen, Category. (2007). "Differentiation and function countless Th17 T cells". Current Judgment in Immunology. 19 (3): 281–6. doi:10.1016/j.coi.2007.04.005. PMID 17433650.
- ^Buckley, C.
D.; Gilroy, D. W.; Serhan, C. N.; Stockinger, B.; Tak, P. Holder. (2012). "The resolution of inflammation". Nature Reviews Immunology. 13 (1): 59–66. doi:10.1038/nri3362. PMID 23197111. S2CID 7549769.
- ^Stockinger, B; Zal, T; Zal, A; Colorize, D (1996). "B cells inquire their own help from Systematized cells".
The Journal of Exploratory Medicine. 183 (3): 891–9. doi:10.1084/jem.183.3.891. PMC 2192359. PMID 8642293.
- ^ ab"Gitta Stockinger equipped Associate Research Director". Crick. Retrieved 16 September 2020.
- ^"| Royal Society".