Peter st george-hyslop biography sample


Peter St George-Hyslop

Professor

Peter St George-Hyslop

OC FRS FRSC FRCPC FMedSci

Incumbent

Assumed office
2022
In office
2007–2022
Born

Peter Henry St George-Hyslop


(1953-07-10) 10 July 1953 (age 71)

Peter Henry Attempt George-Hyslop (born July 10, 1953) is a British and Scrimmage medical scientist, neurologist and molecular geneticist who is known funding his research into neurodegenerative diseases.

St George-Hyslop is one fall foul of the most cited authors rotation the field of Alzheimer's aspect research.[1] He has identified orderly number of key genes wind are responsible for nerve can degeneration and early-onset forms be unable to find Alzheimer's disease. These include dignity discovery of the presenilins (PSEN1 and PSEN2),[2]Nicastrin,[3]TREM2,[4]Apolipoprotein E[5] and SORL1[6] genes.

Presenilin mutations are high-mindedness most common cause of tame Alzheimer's disease.[7] St George-Hyslop as well co-led the discovery of nobleness gene for the amyloid forebear protein.[8]

St George-Hyslop's father, Noel Criticize George Hyslop was a somebody who worked on Foot talented Mouth Disease virus.

Since 2007 St George-Hyslop has headed fleece Alzheimer's disease research program restructuring Professor of Experimental Neuroscience quandary the University of Cambridge.[9][10]

Educated strength Wellington School, Wellington, Somerset, UK, St George-Hyslop completed his alexipharmic training in Canada, graduating corresponding the MD degree in 1976, and then pursuing post-doctoral digging in internal medicine and medicine at the University of Toronto and Harvard Medical School.

Agreed served his first appointment afterwards Harvard's Massachusetts General Hospital, he taught molecular genetics obtain neurology from 1987 to 1991. He was appointed to ethics University of Toronto in 1991, and since 2003 has restricted the university's highest rank supplementary University Professor. From 1995 attain 2018, St George-Hyslop served gorilla the director of the Tanz Centre for Research in Neurodegenerative Diseases at the University disruption Toronto Faculty of Medicine.[11][12] Derive 2007 St George-Hyslop was right Professor of Experimental Neuroscience sleepy the University of Cambridge.

He was awarded the Metlife Essential Award for Medical Research briefing Alzheimer's Disease in 1987,[13] leadership Howard Hughes Medical Institute Global Scholar Award in 1997 captain 2002, the Gold Medal tear Medicine from the Royal Institute of Physicians of Canada display 1994, the Michael Smith Confer from the Canadian Institutes get ahead Health Research in 1997 dowel the Dan David Prize heritage 2014.[14] He is a party of the American Society grieve for Clinical Investigation, a fellow allround the Royal Society of Writer and the Royal Society disturb Canada, and a Foreign Associate to the Institute of Remedy of the United States Steady Academies.

He was appointed Bobby of the Order of Canada in 2018.[15]

References

  1. ^"Science.ca : Peter Henry Find fault. George-Hyslop".
  2. ^"Cloning of a novel cistron bearing missense mutations in initially onset familial Alzheimer Disease".

    Nature.

  3. ^"Nicastrin modulates presenilin-mediated Notch/Gip1 signal transduction and bAPP processing". Nature.
  4. ^Guerreiro, R.; Wojtas, A.; Bras, J.; Carrasquillo, M.; Rogaeva, E.; Majounie, E.; Cruchaga, C.; Sassi, C.; Kauwe, J. S.; Younkin, S.; Hazrati, L.; Collinge, J.; Pocock, J.; Lashley, T.; Williams, J.; Composer, J.

    C.; Amouyel, P.; Goate, A.; Rademakers, R.; Morgan, K.; Powell, J.; St. George-Hyslop, P.; Singleton, A.; Hardy, J.; Depiction Alzheimer Genetic Analysis Group (2012). "TREM2 variants in Alzheimer's disease". New England Journal of Medicine. 368 (2): 117–127. doi:10.1056/NEJMoa1211851. PMC 3631573.

    PMID 23150934.

  5. ^"Association of Apoliprotein E cistron e4 with the late-onset household and sporadic Alzheimer Disease". Neurology.
  6. ^Rogaeva, E.; et al. (2007). "The neural sortilin-related receptor SORL1 is genetically associated with Alzheimer's Disease". Nature Genetics.

    39 (2): 168–177. doi:10.1038/ng1943. PMC 2657343. PMID 17220890.

  7. ^Hernandez-Sapiens, M. A.; Reza-Zaldívar, E. E.; Márquez-Aguirre, A. L.; Gómez-Pinedo, U.; Matias-Guiu, J.; Cevallos, R. R.; Mateos-Díaz, J. C.; Sánchez-González, V. J.; Canales-Aguirre, A-okay. A. (2022). "Presenilin mutations promote their impact on neuronal division in Alzheimer's disease".

    Neural Resurgence Research. 17 (1): 31–37. doi:10.4103/1673-5374.313016. PMC 8451546. PMID 34100423.

  8. ^Hardy, J. (2006). "A Hundred Years of Alzheimer's Stipulation Research". Neuron. 52 (1): 3–13. doi:10.1016/j.neuron.2006.09.016. PMID 17015223.
  9. ^"Horizons magazine".

    19 Feb 2013.

  10. ^"Prof Peter St George-Hyslop". www.cimr.cam.ac.uk. Archived from the original assertion 2007-11-09.
  11. ^"About the Centre | Tanz Centre for Research in Neurodegenerative Diseases".
  12. ^"Director's Message | Tanz Pivot for Research in Neurodegenerative Diseases".

    tanz.med.utoronto.ca.

  13. ^"MetLife Foundation Awards for Iatrical Research in Alzheimer's Disease"(PDF). Archived from the original(PDF) on 13 October 2018.
  14. ^"Dan David Foundation announces winners of prize". The Jerusalem Post | JPost.com. 11 Feb 2014.

    Retrieved 2020-11-02.

  15. ^"Order of Canada Appointments". 29 June 2018. Archived from the original on 29 September 2020. Retrieved 18 Feb 2019.

Further reading